From TIME: “The medical community has been aware of the placebo effect–the phenomenon in which a nontherapeutic treatment (like a sham pill) improves a patient’s physical condition–for centuries. But Ted Kaptchuk, a professor of medicine at Harvard Medical School and one of the leading researchers on the placebo effect, wanted to take his research further. He was tired of letting the people in his studies think they were taking a real therapy and then watching what happened. Instead, he wondered, what if he was honest? His Harvard colleagues told Kaptchuk he was crazy, that letting people in a clinical trial know they were taking a placebo would defeat the purpose. Nevertheless, in 2009 the university’s teaching hospital, Beth Israel Deaconess Medical Center, launched the first open-label placebo, or so-called honest placebo, trial to date, starting with people who had IBS, including Buonanno.
