Childhood Adversity Increases Psychosis
Researchers in the U.K. and Netherlands found a nearly 3x greater chance of childhood adversity among patients with psychosis in 36 studies of various...
Hallucination in the General Population
Investigating the prevalence and types of hallucination-like experiences (HLEs) in a sample of 437 young adults, researchers in Italy, Belgium, the U.K. and Denmark found...
Auditory Hallucinations – Expectation, Interpretation, and Emotion
Researchers in Australia, the U.K., the Netherlands, Canada and Belgium reviewed research on auditory hallucinations (AH) in schizophrenia as well other clinical and nonclinical...
Arkansas’ $1.25 Billion Risperdal Trial Starts Today
Arkansas' lawsuit against Johnson & Johnson for false and misleading claims regarding Risperdal is set to begin today, the fourth time J&J has a...
Rejecting Illness as Chronic Contributes to Better Outcomes
Swiss researchers investigated the paradox that both low and high levels of "insight" are a risk factor for poor outcomes such as depression, hopelessness,...
Theory of Mind and Emotion Processing Training for Schizophrenia
Impairments in social cognition are critical predictors of social functioning in patients with schizophrenia. Emotion processing (EP) and theory of mind (ToM) are hypothesized...
Contribution of Antipsychotics to Suicidality and Depression
Peter Lehmann reviews the contribution of antipsychotics to suicide and depression in schizophrenia in the current International Journal of Psychotherapy. Publications about the intrinsic effects of...
International Society Removes “Schizophrenia” From Its Name
Calling "schizophrenia" an unscientific and stigmatizing construct - with little or no reliability or validity - that implies people with the diagnosis have an irreversible brain...
Polypharmacy and Excessive Dosing
Researchers in Japan investigated 139 patients with schizophrenia diagnoses due to be discharged from 19 acute psychiatric units in Japanese hospitals. Polypharmacy and excessive...
Anhedonia in Schizophrenia Reflects Beliefs, Not Deficits
Researchers at the University of Maryland investigated "the emotion paradox" in schizophrenia; the tendency of individuals with schizophrenia to report similar levels of positive...
Mindfulness-Based Therapy for Psychosis
Researchers in Amsterdam investigated the use of a mindfulness-based therapy for 16 people recovering from a recent experience of first-episode psychosis. 13 completed the...
Recovery Involves Social Support, Self-Reliance, and Trust
Researchers in Brazil followed sixteen individuals after a first-episode psychotic experience to understand their subjective experience of recovery. They found that the participants described...
$1 Billion J&J Settlement Rejected as Insufficient
Federal prosecutors have rejected as insufficient the $1 billion settlement reached two months ago between Johnson & Johnson and prosecutors in Philadelphia to resolve...
MRI Studies
During the 1990s, researchers using MRI technology discovered that antipsychotics shrink the frontal lobes and cause an enlargement of the basal ganglia. In the...
One Hundred Years of Schizophrenia
One Hundred Years of Schizophrenia. Hegerty, J. American Journal of Psychiatry 151 (1994):1409-1416.
In 1994, Harvard Medical School researchers reported that outcomes for schizophrenia patients in the U.S....
The Vermont Longitudinal Study & Correction of Seven Myths
In a long-term study of schizophrenia patients released during the late 1950s and early 1960s from the back wards of Vermont State Hospital, Courtenay...
Schizophrenia: Manifestations, Incidence and Course in Different Cultures
Schizophrenia: Manifestations, Incidence and Course in Different Cultures.Jablensky, A. Psychological Medicine, supplement 20 (1992):1-95.
The second WHO study was called the Determinants of Outcome of Severe...
The International Pilot Study of Schizophrenia
The International Pilot Study of Schizophrenia. Leff, J.Psychological Medicine, 22 (1992):131-145.
The first World Health Organization study that compared schizophrenia outcomes in "developed" and "developing" countries...
Are There Schizophrenics for Whom Drugs May be Unnecessary or Contraindicated?
Are There Schizophrenics for Whom Drugs May be Unnecessary or Contraindicated? Rappaport, M. International Pharmacopsychiatry, 13 (1978), 100-111.
In this 1978 study, Maurice Rappaport and his colleagues at...
The Treatment of Acute Schizophrenia Without Drugs
The Treatment of Acute Schizophrenia Without Drugs. Carpenter, W. American Journal of Psychiatry, 134 (1977), 14-20.
In this 1977 NIMH study, 49 schizophrenia patients placed into an experimental...
Comparing five-year outcomes in the pre-Thorazine era and the post-Thorazine era.
Comparison of Two Five-Year Follow-up Studies.Bockoven, J. American Journal of Psychiatry, 132 (1975), 796-801.
In this study, Boston psychiatrists Sanbourne Bockoven and Harry Solomon compared relapse rates...
Relapse in Chronic Schizophrenics following Abrupt Withdrawal of Tranquilizing Medication
Relapse in Chronic Schizophrenics following Abrupt Withdrawal of Tranquilizing Medication. Prien, R. British Journal of Psychiatry, 115 (1968), 679-86.
The critical finding of this NIMH study was that...
Ongoing Brain Changes With Antipsychotic Treatment
Nancy Andreasen's 2003 study finding ongoing brain changes in persons with schizophrenia diagnoses, despite antipsychotic drug treatment.
Article → ...
Are There Schizophrenics for Whom Drugs May be Unnecessary or Contraindicated?
1978 study of 80 young males diagnosed with acute schizophrenia, finding that "many unmedicated-while-in-hospital patients showed greater long-term improvement, less pathology at follow-up, fewer...
No Evidence for Antipsychotics’ Efficacy
In a review of 681 studies comparing use of antipsychotic medication with placebo, milieu, or psychosocial treatment in first- or second-episode schizophrenia spectrum disorders,...
