Early Intervention

A new study to be published in the next issue of Schizophrenia Research examines patients suffering from a first-episode of psychosis who stop taking any antipsychotic drugs. The researchers attempt to identify variables that can serve as predictors of the successful discontinuation of antipsychotics. They find, for example, that those who discontinue the drugs have, on average, the same outcomes as those who stay on them, and that those who have better social integration are more likely to discontinue without relapse.

Columnist Nev Jones writes about the lack of adequate care for people in the US experiencing a first-episode of psychosis. “Evidence-based (or informed) psychotherapies...

There is a substantial body of evidence suggesting that not getting enough omega-3 fatty acids in your diet may be connected to a diverse array of psychiatric symptoms. In a new study published this month, psychiatrist Robert McNamara and Erik Messamore provide an overview of the evidence and call for screening of omega-3 deficiency in people experiencing symptoms associated with ADHD, depression, mood disorders, and psychosis.

A pathbreaking new study out of Finland suggests that early intervention programs for youth experiencing psychotic-like symptoms may see the greatest improvement when treatment works within the home rather than in a hospital setting. The research, to be published in next month’s issue of Psychiatry Research, found greater improvement in functioning, depression, and hopelessness among teens in a new need-adapted Family and Community oriented Integrative Treatment Model (FCTM) program.

A study published in this month’s issue of the Social Psychiatry and Psychiatric Epidemiology found that perceived discrimination related to minority status may precede...

"It's no secret that stimulant medications such as Adderall that are prescribed to treat symptoms of ADHD are sometimes used as 'study drugs' aimed...

“The fact that drinking sugar or exposure to early life stress reduced the expression of genes critical for brain development and growth is of...

Benedict Carey of the New York Times reports on the success of new schizophrenia and psychosis programs that provide family counseling and job and...

"Eleanor Longden started hearing voices when she was 18. She was drugged and hospitalised, then told she was schizophrenic. A psychiatrist even told her...

MIA contributor Jonathan Leo, writing for Slate, weighs in on the research that claims to have discovered a genetic basis for schizophrenia. “We now...

The case of “Beth” depicts, almost innocently, the trials and tribulations of a well-adjusted, talented 15-year-old who developed depression, paranoia, panic attacks, and self-injurious and homicidal behavior, and “bipolar disorder” after being prescribed antidepressants, and then antipsychotics. After Beth decided - on her own - to discontinue psychotropic medications in favor of hormone therapy, she remained free of psychiatric symptoms.

Last week, the headlines blared: "Schizophrenia breakthrough as genetic study reveals link to brain changes!"  We heard that our best hope for treating “schizophrenia” is to understand it at a genetic level, and that this new breakthrough would get us really started on that mission, as it showed how a genetic variation could lead to the more intense pruning of brain connections, which is often seen in those diagnosed with schizophrenia.  “For the first time, the origin of schizophrenia is no longer a complete black box,” said one (while admitting that "it's still early days").  The acting director of the National Institute of Mental Health (NIMH) described the study as “a crucial turning point in the fight against mental illness.” But is all this hype justified?

In a study published yesterday, researchers from the Nippon Medical School in Tokyo bring attention to a condition known as neuroleptic-induced deficit syndrome (NIDS)...

Dutch psychiatrist and epidemiologist, Jim van Os, has renewed his call to drop schizophrenia as a disease classification. “Several recent papers by different authors...

“Overall, this study showed that the information and awareness campaign had almost no significant effects on the general public's attitudes toward people affected by either schizophrenia or depression,” the researchers, led by German medical sociologist Anna Makowski, wrote. “One could assume that deeply rooted convictions cannot be modified by rather time-limited and general activities targeted at the public.”

In recent months, two teams of researchers in the UK and the US published complementary findings about the epigenetic origins of schizophrenia that have scientific communities who indulge in ‘genetic conspiracy theories’ abuzz. While these results are intriguing, and no doubt involve pathbreaking research methodologies, this line of thought represents a decontextualized understanding both of the symptoms that are typically associated with schizophrenia, and their causes.

A study out of the University of Buffalo explores the use of Narrative Exposure Therapy to treat youth PTSD and substance abuse. “Trauma is...

“Children from poorer families are more likely to experience changes in brain connectivity that put them at higher risk of depression, compared with children from more affluent families,” according to new research covered by Medical News Today. "Poverty doesn't put a child on a predetermined trajectory, but it behooves us to remember that adverse experiences early in life are influencing the development and function of the brain. And if we hope to intervene, we need to do it early so that we can help shift children onto the best possible developmental trajectories."

In this month’s issue of Psychological Medicine, researchers from King’s College London found evidence for associations between different types of childhood adversity and specific symptoms associated with psychosis. As current categorical approaches to psychosis and schizophrenia diagnoses come under increasing scrutiny, this study adds support to sociological and psychological theories and treatments.

The Boston Globe reports on the discovery of a newly recognized neurological disease, anti-NMDA receptor encephalitis. The disease is believed to be caused when the body’s immune system attacks proteins in the brain associated with the communication of neurons.

PsychCentral covers new research linking social deprivation, population density and inequality with higher rates of psychotic symptoms and diagnoses for schizophrenia. “This is important because other research has shown that many health and social outcomes also tend to be optimal when societies are more equal.”

The Guardian covers research out of Australia that found that levels of the “stress hormone” cortisol in the hair of 70 nine-year-old children corresponded to the number of traumatic events experienced by the child. “Childhood is an imperative and sensitive period of development, and when things go wrong it can have lifelong consequences, not just on mental health, but also on general health.”

“A little background digging revealed to me that this study is the tip of a new iceberg relative to ADHD diagnosis, stimulant treatment, and...

In the SundayReview section of the New York Times Vicki Abeles discusses Stuat Slavin’s research on depression and anxiety in US schools. “Many of the health effects are apparent now, but many more will echo through the lives of our children,” says Richard Scheffler, a health economist at the University of California, Berkeley.

“Do they make people less aggressive? Yes, sometimes they do. Will they sedate people? Absolutely. Will they make kids easier to manage? They will,” Robert Whitaker tells Liz Spikol for Philadelphia Magazine. “But I know of no study that shows that medicating these kids long-term will help them grow up and thrive. The developing brain is a very delicate thing. The narrative is that these side effects are mild, and that’s just not true, and that the benefits are well-established, and so often they’re not.”