Genetic Markers do not Predict Response to Antidepressants

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Researchers from 11 nations in Europe and North America find, in the largest study to date of possible links between genetic markers and antidepressant...

Pfizer Settles First of 2,600 Claims Regarding Chantix and Suicide

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After failing to win a postponement earlier this week, Pfizer settled with the widow of Minnesota man who suicided while using the stop-smoking drug...

New IRIS Guidelines for Early Intervention in Psychosis

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The 'Initiative to Reduce the Impact of Schizophrenia" (IRIS) has updated its 1998 guidelines for early intervention in psychosis to state that not all people...

On Deciphering Recovery for the American Psychiatric Association: Lecture on 13 Innovations to Improve...

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How did the APA talk go? Overall a success-- the audio went viral on the internet, and the talk itself was so crowded we had to move to a larger room -- more than 70 psychiatrists and behavioral healthcare professionals attended. Afterwards many stepped up to shake my hand and congratulate me: I was told by two people I was a gift to the conference, asked to present at a Grand Rounds, encouraged to do a TED talk, thanked for my compassionate response to a question about forced treatment, and invited to do more trainings in the future. I even met several psychiatrists who are Madness Radio listeners. Psychiatry is clearly not a monolithic profession and many in it are beginning to think differently.

“Serious Breakdown” on Cymbalta Withdrawal Warnings

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"The last four years have seen a 90% increase in the number of serious adverse drug reports received by the Food and Drug Administration," according to a report by the Institute for Safe Medication Practices." Among them, a "signal" that Cymbalta causes "an array of problems such as crying, suicidal ideation, and anger, and other symptoms including effects on appetite and weight gain."

Crowdfunding Science

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Scientific American explores a crowdfunded approach to researching methamphetamine addiction, suggesting the approach is adaptable to pursuing other questions that are challenged to find...

Psychiatry is “Committing Professional Suicide”

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David Healy "likened psychiatry’s attitude toward its faltering legitimacy to the Vatican’s widely derided response to its child sex abuse scandal by priests —...

Global Pharmaceutical Industry Fined $11 Billion in Three Years

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Although the global pharmaceutical industry racked up $11 billion in fines in the last three years, "Companies might well view such fines as a...

J&J Alleged To Hide Evidence That Risperdal Grows Boys’ Breasts

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"A drug that was never meant for kids was illegally marketed to kids," said a lawyer for the plaintiff in opening remarks for the...

Mental Health Rights, Pharma, and the Election

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Jim Gottstein writes in Pharmalot about developments in the mental health rights field, how pharma has contributed (positively or negatively), and how the upcoming...

Risperdal Whistle-Blower Honored in Texas, Fired in Pennsylvania

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Allen Jones, the whistle blower whose testimony resulted in a $158 million settlement by Johnson & Johnson for fraudulent marketing of Risperdal in Texas,...

Psychotropics Drive Record 4.02 Billion U.S. Prescriptions in 2011

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With drugs for ADHD increasing 17%, and an "unprecedented increase in patients taking antidepressants and antipsychotics," overall prescription drug sales in the United States...

Thomas Szasz, April 15, 1920 – September 8, 2012

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Thomas Szasz, relentless "critic of coercive psychiatry, the 'therapeutic state,' and the war on drugs," died at his home in Manlius, N.Y. over the...

Off-Label Antipsychotic Use Among Children Soaring

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Researchers from Philadelphia and Baltimore find, in a study of Medicaid records for 50 states and the District of Columbia, that antipsychotic prescribing to...

Former FDA Counsel: J&J Settlement ‘Is Huge’

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In an interview with Pharmalot, former FDA associate chief counsel Arnie Friede discusses the impact of last month's $181 million Risperdal settlement on pharmaceuticals'...

J&J Settles Risperdal Lawsuit on Opening Day

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Johnson & Johnson settled one of about 420 Risperdal-related lawsuits on the trial's opening day. "The case is resolved and the client is satisfied,"...

Eli Lilly is Overvalued

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The investment newsletter Seeking Alpha reports that Eli Lilly's research woes, including the halting of research into a new antipsychotic, mean that Lilly's stock...

“Grief is Good News for Pharmaceutical Companies”

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The U.K.'s Guardian writes today that "the proposal by the American Psychiatric Association to create a new illness – prolonged grief disorder – and...

Top Docs Call Psych Diagnoses by Brain Scans “Modern Phrenology”

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The Washington Post profiles Daniel Amen, "the most popular psychiatrist in America," who claims in copious books, DVDs, television and speaking engagements to be...

South Dakota Court Revives Cymbalta Suicide Case

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A federal appeals court has reversed a lower court's summary judgment in favor of Eli Lilly,   allowing the parents of a South Dakota...

NIH Defends Nemeroff Grant, Issues Talking Points

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When it awarded yet another multimillion-dollar grant to Charles Nemeroff, a key figure in the controversy over conflicts of interest involving pharmaceutical research, U.S....

NE Journal of Medicine Backs Congressional Call for Research Transparency

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Rep. Ed Markey (D-MA) introduced the Trial and Experimental Studies Transparency (TEST) Act into congress on August 2, 2012; a bill aimed at closing...

Nineteen New Zoloft Birth Defect Lawsuits Filed

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Nineteen defective drug product liability cases against Prizer have been filed in West Virginia state court by mothers alleging that their children suffered from...

BJP Announces “The End of the Psychopharmacological Revolution”

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The editor of the British Journal of Psychiatry, in a comment on Morrison et al.'s "Antipsychotics: is it Time to Introduce Patient Choice," announces...

Pharma Execs Barred from Federal Programs

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Three former executives from Purdue Pharma have been barred by a federal appeals court from doing business with federal healthcare programs such as Medicare...