Medication Tapering/Withdrawal

A new study to be published in the next issue of Schizophrenia Research examines patients suffering from a first-episode of psychosis who stop taking any antipsychotic drugs. The researchers attempt to identify variables that can serve as predictors of the successful discontinuation of antipsychotics. They find, for example, that those who discontinue the drugs have, on average, the same outcomes as those who stay on them, and that those who have better social integration are more likely to discontinue without relapse.

Last year the British Medical Association (BMA) released a report on dependence and withdrawal from prescription drugs including benzodiazepines, z-drugs, opioids, and antidepressants. Now,...

For a long time I have felt that there just isn’t a good enough and long enough study on the pros and cons of long-term antipsychotic treatment versus reduction and discontinuation in people who have psychotic disorders, including those who are classified as having schizophrenia. Moreover, there are increasing reasons to be worried about the effects of long-term treatment with antipsychotics. I put this case to the UK’s National Institute of Health Research recently, and proposed that they fund a trial to assess the long-term outcomes of a gradual programme of antipsychotic reduction compared with standard ‘maintenance treatment.’ The NIHR agreed that this was an important issue, and that a new trial was urgently needed. The RADAR (Research into Antipsychotic Discontinuation And Reduction) study officially started in January 2016.

“Two Scots whose lives have been ravaged by prescription drugs are battling for ­recognition of the devastating withdrawal issues as well as proper support for victims,”...

Psychologist and Professor Amber Gum has published the story of her personal journey of rethinking psychotropic medication in a special issue on "The Politics of Mental Health" in The Journal of Medicine and the Person. Influenced by Mad in America and the work of Robert Whitaker, Gum became aware of evidence that “suggests that psychotropic medications are less effective and more harmful than most believe” and now hopes to encourage other mental health professionals and researchers to engage in open-minded, critical self-assessment of standard practices.

“A quick look at drugs or drug uses that later turned out to be risky shows a disturbing trail of ‘bought’ science in major medical...

Revealing the false information provided about psychiatry should cause any thinking person, patient, thought-leader or politician to wonder: “how many otherwise normal or potentially curable people over the last half century of psych drug propaganda have actually been mis-labeled as mentally ill (and then mis-treated) and sent down the convoluted path of therapeutic misadventures – heading toward oblivion?”

“CBS News went to West Virginia, a state that is attempting a drastic solution: allowing addicts to sue the doctors who got them hooked.”

My doctor insisted that my symptoms could not be associated with withdrawal – they had to be symptoms of an underlying condition. I have since learned from legitimate sources that protracted withdrawal syndrome from benzodiazepines can intensify long before it abates, with some symptoms lasting for years.

Researchers from the City College of New York and Columbia University published a study this month testing the hypothesis that people diagnosed with schizophrenia treated long-term with antipsychotic drugs have worse outcomes than patients with no exposure to these drugs. They concluded that there is not a sufficient evidence base for the standard practice of long-term use of antipsychotic medications.

An analysis of medical records in the UK reveals that the use of certain antidepressants for depression is linked to a heightened risk for mania and bipolar disorder. The research, published this week in BMJ Open, found the strongest effect for serotonin reuptake inhibitors (SSRIs) and the antidepressant venlafaxine.

In a major study, published yesterday in JAMA Pediatrics, the use of SSRI antidepressants during pregnancy was found to increase the risk of autism spectrum disorder (ASD) by 87-percent. Previous studies reveal that more than 13-percent of women currently use SSRI antidepressants during pregnancy.

A new poll, published in the Washington Post, explores the public’s connection to prescription pain killer abuse. “A surprising 56 percent of the public say...

When language has been ingrained in a culture for a long time, it takes a concerted effort to change it. How do we stop using the word “addiction” in relation to cases of iatrogenic benzo dependence? Here are a few suggestions.

Language is important. And when language dictates specific treatment protocols, it should be used with extreme scrutiny. Using the wrong words can put vulnerable people at risk—not only to their sense of self-worth, their sense of self-knowledge, and they way they are treated, but also to their health.

In 2014, then National Institute of Mental Health (NIMH) director, Thomas Insel, speculated that ketamine “might be the most important breakthrough in antidepressant treatment in decades.” A recent review of the research suggests that while ketamine may produce a rapid short-term improvement in depression, the effect is short-lived and the potential for addiction and dependence warrants considerable caution.

I was a psychiatrist who participated in the Recovery After an Initial Schizophrenia Episode Early Treatment Program (RAISE ETP). Although I welcomed the positive headlines that heralded the study's results, the reports left me with mixed feelings. What happened to render the notion that talking to people about their experiences and helping them find jobs or go back to school is something novel?

Despite safety concerns, a new study reveals that there has been no change in the use of benzodiazepines in the elderly from 2001 to 2010.

This week the drug monitoring and patients' rights website, RxISK, launched the Centre for Medication Withdrawal, a page dedicated to establishing what causes dependence and how to treat it.

Statistics from the UK reveal that prescriptions for painkillers and antidepressants continue to rise despite concerns over dependence and debilitating withdrawal effects. The British Medical Association (BMA) Board of Science has released a report that acknowledges changes to medical practice, research and policy necessary for addressing the dependence and withdrawal effects of benzodiazepines, opioids, and antidepressants.

Healing mental health issues through correct supplements as well as nutrition is, I believe, the final factor for me in my journey. This is possibly what was missing in my first attempt at coming off, and why my brain and body couldn’t handle the extreme anxiety I felt in December 2013. I am ensuring that as I prepare to taper off the Lexapro in 2015, my brain and body are being supported in every way possible.

Many people now using psychiatric drugs have been convinced or forced to use them while being treated in the mental health system. A good number of people are eager to stop using these drugs, but are often discouraged by others from doing so. Many psychiatric survivors believe that they can never stop using these drugs because they were told they would need to use them the rest of their lives. We hope the Sunrise Center will become a catalyst for a movement of people creating places for people who want to stop using psychiatric drugs.

I’ve been working steadily on Cracked Open, a book that chronicles my experience being a mother suffering terrible insomnia to a mother desperately dependent on benzodiazepines. I am not alone. I live in a state that ranks at the top for anti-depressant and anti-anxiety meds and we love to give them to women. But I’m not writing this book simply for mothers or for women. I’m writing it for anyone who has gone into a doctor’s office, desperate and sick, and come out with a prescription that led them down a path to illness and/or disability. It happens so often.

This is the second of a series of excerpts from Cracked Open, a book whose unintentional beginning came after I became physically dependent on Ativan in 2010. After a year of following my doctor’s orders for daily use to treat insomnia, my body and mind began to fall apart. I’m serializing the book here – before sending it out into the world – because MIA became a lighthouse for me. I want this community’s feedback because I want to help make a difference. I want my words and message to be clear and strong.

This is the first of a series of excerpts from Cracked Open, a book whose unintentional beginning came after I became addicted to Ativan in 2010. After a year of following my doctor’s orders for daily use to treat insomnia, my body began to fall apart. My story is much like the stories I’ve read on MIA.