Research News

Summaries of research findings that tell of a scientific need to "rethink psychiatry."

Paranoid Symptoms Arise From Social Phobia/Trauma

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In a 10-year longitudinal study of 3021 participants, researchers in The Netherlands, U.K., Germany and Switzerland find that paranoid symptoms are associated with social...

Schizophrenia, Trauma and The Immune System

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To test the hypothesis that a heightened immune system response associated with schizophrenia is also associated with childhood trauma, researchers in Ireland looked at...

Antipsychotics for Dementia: Not Justified and Risky

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In a study of antipsychotics used to treat 75,445 patients in nursing homes in the United States, researchers from Harvard Medical School, Columbia and...

NH Wins $10 Million to Expand Fitness Program

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New Hampshire's SHAPE program to promote physical fitness for the mentally ill has been so successful that the federal government has awarded $10 million...

Better Recovery and Less Relapse Without Meds: A 20-Year Study

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Researchers at the University of Illinois College of Medicine found, in a 20-year prospective study of 139 psychotic patients, that patients had a far...

Psychosis as a Basic “Disturbance of Self”

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Researchers in Australia and the U.K. found that a basic disruption of the sense of ownership of one's experience and a lack of self-agency...

Criticism of the DSM Goes Mainstream

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Criticism of the upcoming revision of the DSM has gone mainstream, with Forbes Magazine weighing in on the economics of medicalizing grief, and Fox News questioning the...

Psychosis in the General Population

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Schizophrenia Bulletin explores "the extended psychosis phenotype," finding that affective dysregulation, psychotic experiences, motivational impairments, and cognitive alterations are distributed throughout the population, and suggestive...

Psychosis Overlaps With Anxiety and Depression

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In a representative community sample of 3021 adolescents and young adults, researchers in The Netherlands, Germany, Switzerland, and the U.K. found that 27% of...

Schizophrenia Bulletin Questions the “Psychosis Phenotype”

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In an editorial introducing its March issue, Schizophrenia Bulletin explores the categorical distinctions that have defined and directed research into psychotic disorders since the late 19th...

60 Minutes to Cover Antidepressant/Placebo Controversy This Sunday

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Lesley Stahl interviews Irving Kirsch of the Placebo Studies Program at Harvard Medical School this Sunday's edition of 60 Minutes. Stahl says the implication...

Some Avoid Antipsychotics Because They Value Psychosis

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Side effects, mistrust, stigma, forgetfulness and lack of insight have all been studied as reasons that up to 75% of people with a schizophrenia...

Mindfulness-Based Cognitive Therapy is Effective in Bipolar Disorder

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Researchers at Massachusetts General Hospital and Harvard Medical School found that Mindfulness Based Cognitive Therapy increased mindfulness, lowered depressive mood symptoms, lessened attentional difficulties,...

Childhood Maltreatment Reduces Hippocampal Volume

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Researchers at Harvard University, in the largest and most detailed study on the topic to date, found that childhood maltreatment is significantly associated with...

Benzo Discontinuation Improves Quality of Life and Reduces Symptoms of Schizophrenia

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Researchers in Japan find that tapering or reducing benzodiazepines has a positive effect on quality of life, verbal and working memory, and psychiatric symptoms...

Non-Drug Therapies Outperform Drug Therapies in Preventing Relapse

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In a study of 597 outpatients who were perceived as likely nonadherers to oral antipsychotic interventions, Spanish researchers found that relapse was lower in...

Beliefs About Illness and Rehabilitation Predict Outcome in Depression

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Researchers in Germany found that in a sample of 98 patients, beliefs about illness and rehabilitation predicted outcome for depression independent of medical or...

Antidepressants Have No Effect On Bipolar Depression

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In a review of 68 articles published between 2005 and 2011, Israeli researchers found that most well-controlled studies failed to show a significant effect of...

African-Americans More Likely to be Diagnosed Schizophrenic

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In a study of 610 psychiatric inpatients and outpatients from six academic medical centers across the United States, African Americans were almost three times...

England Seeks to Stop Antipsychotics For Dementia

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English health minister Paul Burstow is seeking to outlaw the 'silent scandal' of inappropriate antipsychotics for dementia by proposing legislation that imposes up to...

Antipsychotic Use Does Not Correlate With Conversion to Psychosis

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Researchers in Brazil find, in a meta-analysis, that only 30% of youth deemed to be of ultra high risk of psychosis do in fact...

David Healy Critiques Gibbons’ Reanalysis of Antidepressants and Suicide

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David Healy critiques the reanalysis by Robert Gibbons of antidepressants and suicidality in children and adolescents that was reported on this page yesterday. He...

Cognitive Therapy Shown to be Effective For Schizophrenia

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Researchers report in the February issue of Archives of General Psychiatry that cognitive therapy improved both positive and negative symptoms in "low-functioning" patients with...

Suicidal Thoughts and Behavior With Antidepressant Treatment: A Reanalysis

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In 2004 and 2006, the FDA concluded that SSRI antidepressants increased the risk of suicidal ideation in children and adolescents. However, in this month's...

Lawsuit Filed for Alleged Zoloft-Related Birth Defects

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Lawyers in St. Louis have filed a lawsuit against Pfizer that alleges 18 children were born with birth defects caused by the antidepressant Zoloft...