Antidepressants Increase Risk of Death, Study Finds
Antidepressants are commonly considered safe and effective treatments. However, research has questioned their efficacy, and now, their safety.
Replacing Pain with Pain: Hazards of Antidepressant Use for Chronic Pain Relief
The paradox of relieving chronic pain with an antidepressant (and a new set of symptoms).
Study Suggests Mania More Common in Psychosis When Antidepressants Used
A prospective cohort study of those labeled high risk for psychosis finds a higher prevalence of antidepressant use among those who develop manic symptoms.
Researchers Identify Patterns in Antidepressant and Long-Term Benzodiazepine Use
The researchers found that, of those who were initially prescribed both antidepressants and benzodiazepines, approximately 12% went on to engage in long-term benzodiazepine use.
Over 1,000 Antidepressant Users Describe how Their Personal Life has Been Affected
Survey examines adverse personal and interpersonal effects of antidepressants and the impact of polypharmacy
Study Investigates Physicians’ Beliefs About Placebo and Nocebo Effects of Antidepressants
Surveyed doctors overestimate pharmacological effects of antidepressants and underestimate placebo effects.
PTSD and Psychiatric Medication Linked to Dementia in Older Veterans
Veterans diagnosed with PTSD and taking SSRIs, novel antidepressants, or atypical antipsychotics are more likely to develop dementia.
Researchers Search for Subgroups Where Antidepressants Are More Effective
The researchers theorized that this increased effectiveness was due not to “antidepressant” properties, but rather to the drug’s side effects, which include insomnia, drowsiness, and nausea.
Could ‘Treatment Resistance’ be an Effect of Antidepressants?
Previously taking antidepressants could make individuals less likely to respond to treatment for bipolar II depression.
‘Do Antidepressants Work?’ is the Wrong Question
“This research points to the inadequacy of asking the simple question: ‘Do antidepressants work?’ Instead, the value or otherwise of antidepressants needs to be understood in the context of the diversity of experience and the particular meaning they hold in people’s lives.”
Most Off-Label Prescribing of Antidepressants Lacks Strong Scientific Evidence
A new study, published in the British Medical Journal, investigates the prevalence of off-label prescribing for antidepressant medication in primary care settings.
New Data Show Lack of Efficacy for Antidepressants
An article published this month in the journal BMC Psychiatry suggests that there is a lack of efficacy for SSRIs and that they significantly increase the risk of serious side effects.
Antidepressant use During Pregnancy may Increase Risk of Birth Defects
Use of antidepressants increased the risk of organ-specific malformations in women with depression
Antidepressant Use May Increase Risk of Hip Fractures in Older Adults
Study finds antidepressant use is linked to increase in hip fractures in community-dwelling older adults with and without Alzheimer’s disease.
Withdrawal from Antidepressants
A review of the scientific literature related to withdrawal from antidepressants: mechanism of action; long-term effects of exposure to antidepressants; discontinuation syndromes; relapse upon discontinuation; tapering protocols.
What Animal Research Says About Sexual Side-effects of SSRIs
A group of researchers in Denmark examines what existing animal studies can tell us about the sexual side-effects of SSRI antidepressants.
Antidepressant Use Linked to Dementia
A new study finds that elderly individuals using antidepressants are at significantly higher risk for dementia compared to depressed individuals who did not take the drugs.
Study Finds Antidepressants in Pregnancy Increase Risk for Speech Disorders
A new study published this week in JAMA Psychiatry indicates that infants are more likely to develop speech or language disorders if they are exposed to antidepressants during pregnancy.
Systematic Review Finds Antidepressants Double the Risk for Agitation and Violence in Healthy Volunteers
The Nordic Cochrane Center conducted a systematic review of existing research trials on antidepressants and found that the drugs doubled the risk of feelings...
Use of Antidepressants Linked to Diabetes
Selective serotonin reuptake inhibitors (such as Prozac and Zoloft) are the most commonly prescribed medication for depression. SSRIs have long been associated with an...
Clinical Trials Underreport Harms of Antidepressant Medications
A group of researchers recently found serious bias in the reporting of harm due to adverse events in antidepressant medication clinical trials. They report...
Antidepressants in Pregnancy: Risks to the Fetus and Long-term Health of the Child
The research literature reveals that antidepressant use in pregnancy poses considerable risks to the fetus and the long-term health of the child. These risks include preterm birth, birth defects, abnormal brain development, and behavioral abnormalities in early childhood.
How Do Antidepressants Really ‘Work’?
A recent review, published in Neuroscience & Biobehavioral Reviews, challenges the dominant assumptions about the neurochemical and therapeutic effects of Selective Serotonin Reuptake Inhibitors...
Antidepressant Effects Thwarted by Stressful Environments
A new study, about to be published in the journal Brain, Behavior, and Immunity, investigates the role a stressful environment plays in antidepressant effectiveness....
Review Calls for Critical look at Prescribing Antidepressant Drugs
The August issue of Psychotherapy and Psychosomatics published a review conducted by André F. Carvalho and colleagues regarding the literature around the long-term use...
