Disconnect Between Antipsychotic Prescribing and Metabolic Screening
Despite American Diabetes Association and APA recommendations of glucose and lipid testing for all patients started on antipsychotics, there is a disconnect between prescribing...
Baseline Lipid Monitoring with Antipsychotics “Disappointingly Low”
"Even in an academic setting with active discussions among psychiatrists regarding issues of metabolic risk ... baseline lipid monitoring is disappointingly low" according to...
Pharmacology Gets More Cooperation Than Psychosocial Advice
In a study of conformance to evidence-based treatment recommendations at mental health clinics among people diagnosed with schizophrenia, Canadian researchers found that conformance to...
Most Cases of Tardive Dyskinesia are Permanent
Only one out eight patients, out of 108 with tardive dyskinesia, recovered from the disorder in an Emory University Movement Disorders Clinic study. The...
Schizophrenia Prevents Cancer; Antipsychotics May Cause It
In a review of all 59,233 individuals diagnosed with schizophrenia in Sweden between 1965 and 2008, researchers from Sweden and the U.S. identified 6137...
Pharmacological Treatment of Schizophrenia: a Fifty-Year Review
Researchers in the U.S. and India reviewed the pharmacological treatment of schizophrenia since its introduction 50 years ago, trying to understand why it "remains...
Multiple Medications Associated With Poorer Outcomes
Research from Germany finds that people with schizophrenia or schizoaffective diagnoses given multiple medications - an antipsychotic plus a benzodiazepine or more than one...
No Advantage for Second-Generation Antipsychotics
In a study of 720 consecutive hospital admissions in a specific catchment area from 1991 to 2005, researchers found that there was no difference...
Prenatal Antipsychotic Exposure Causes Neuromotor Deficits
Researchers studying 309 6-month-olds at Emory University's Infant Development Laboratory found that infants prenatally exposed to antipsychotics showed significantly lower scores on a standardized...
Antipsychotics Increase Risk of Heart Attack in the Elderly
In a study of 10,969 older patients treated with antipsychotics in Quebec, Canada, researchers found a 2.19 times greater risk of heart attack in...
Second-Generation Antipsychotics Just as Likely as Older Drugs to Cause EPS
In a study of an earlier randomized controlled trial of antipsychotics, researchers from Yale and the U.K found that second-generation antipsychotics were as likely...
Psychiatric Drugs, Especially Antipsychotics, Contribute to Increasing Drug Costs
Antipsychotics have overtaken antidepressants as the most costly class of psychiatric medication in England, according to a study by Stephen Ilyas and Joanna Moncrieff...
Contribution of Antipsychotics to Suicidality and Depression
Peter Lehmann reviews the contribution of antipsychotics to suicide and depression in schizophrenia in the current International Journal of Psychotherapy. Publications about the intrinsic effects of...
Seroquel Abuse Rising, Along With Ambulance Calls
Australian researchers have uncovered an alarming increase of Seroquel-related ambulances calls. Rising prescriptions of of the drug along with its developing use as a drug...
High Cost to Medicaid Programs For Off-Label Use of Antipsychotics
A study of 42 state Medicaid programs found that 58% of prescriptions for antipsychotics were not for schizophrenia or bipolar disorder. Off-label prescribing was most prevalent...
45% of Children and Adolescent Inpatients Prescribed Antipsychotics
In a rare long-term study of antipsychotics used in children and adolescent inpatients, the Institute of Living in Hartford, CT followed 3,851 consecutive admissions...
WHO Says Newer Antipsychotics Most Costly, Least Effective Strategy
In an analysis of neuropsychiatric conditions in sub-Saharan Africa and South East Asia, the World Health Organization found that inpatient treatment of schizophrenia with...
Rise of Antipsychotics in Children
Researchers at Johns Hopkins explore the use of antipsychotics in children, finding a dramatic rise in off-label prescribing with little oversight or research into...
Risk of Death in the Elderly Trebled With Antipsychotics
In a nine-year study of all 2,224 residents of Leppävirta, Finland who were 65 years old or older, researchers found that the 332 residents...
Cumulative Risk of Impairment and Death From Anticholinergic Medication
The New York Times reports that a two-year longitudinal study of over 13,000 men and women over 65 found that anticholinergic medications, which include many...
Antipsychotics for Dementia: Not Justified and Risky
In a study of antipsychotics used to treat 75,445 patients in nursing homes in the United States, researchers from Harvard Medical School, Columbia and...
Better Recovery and Less Relapse Without Meds: A 20-Year Study
Researchers at the University of Illinois College of Medicine found, in a 20-year prospective study of 139 psychotic patients, that patients had a far...
Some Avoid Antipsychotics Because They Value Psychosis
Side effects, mistrust, stigma, forgetfulness and lack of insight have all been studied as reasons that up to 75% of people with a schizophrenia...
Non-Drug Therapies Outperform Drug Therapies in Preventing Relapse
In a study of 597 outpatients who were perceived as likely nonadherers to oral antipsychotic interventions, Spanish researchers found that relapse was lower in...
Antipsychotic Use Does Not Correlate With Conversion to Psychosis
Researchers in Brazil find, in a meta-analysis, that only 30% of youth deemed to be of ultra high risk of psychosis do in fact...
